ライフサイエンスコーパス: NEP

1 NEP activity was histochemically localized in several, b

2 NEP can be accessed on the internet at http://exon.niaid

3 NEP cells possess gap junctions, express connexins, and

4 NEP cells, however, lacked expression of several lineage

5 NEP decreased with increasing temperature at all low Arc

6 NEP delivery bypassed endocytosis by electrophoretic inj

7 NEP loss of function 1) elevated whole-brain and plasma

8 NEP was jointly determined by GPP and Re for both inland

9 NEP was not inactivated to a significant extent by HNE,

10 NEP-like activity has also been found in the brain of se

11 sly inhibit both neutral endopeptidase 24.1 (NEP) and ACE.

12 grass NEP (median: 20.6 mmol C m(-2) d(-1)), NEP in grazed Caribbean T. testudinum meadows is similar

13 Neutral endopeptidase 24.11 (NEP) is a cell surface peptidase expressed by numerous t

14 Neutral endopeptidase 24.11 (NEP) is a cell-surface peptidase that cleaves and inacti

15 e ectodomain of neutral endopeptidase 24.11 (NEP).

16 sites were net sinks for atmospheric CO(2) (NEP ranged from 5 to 67 g C m(-2)), with low Arctic site

17 provide the proof of concept that BMN 111, a NEP-resistant CNP analog, might benefit individuals with

18 a novel pharmacologic agent that combines a NEP inhibitor and an angiotensin receptor blocker.

19 pro-drugs, derived from co-drugs combining a NEP and an APN inhibitor through a disulfide bond with s

20 We developed a NEP fusion protein with in vitro degradation of Abeta an

21 enalapril (10 mg BID, n=2884) or to the ACE-NEP inhibitor omapatrilat (40 mg once daily, n=2886) for

22 concordance between self-reported and actual NEP use; 11.0% reported NEP attendance but did not atten

23 erns, how groundwater accessibility affected NEP was more complex than ET.

24 Again, NEP was localized to regions of the neuropil that also d

25 beit lacking the desired selectivity against NEP.

26 scribe the implementation of this algorithm, NEP (Neutralization-based Epitope Prediction), as a web-

27 Although NEP stimulates viral RNA synthesis by binding to the vir

28 ve reported higher HIV incidence rates among NEP attendees.

29 tation was above normal as effects on ER and NEP offset one another.

30 s demonstrated coherent responses of GEP and NEP to anomalies in annual evapotranspiration (ET), used

31 Since IDE and NEP play a prominent role in the clearance of amyloid be

32 Our studies indicate that Kell and NEP use the same homologous amino acids in the coordinat

33 xtract induced liver, but not brain, LRP and NEP and decreased plasma and brain Abeta, indicating tha

34 wever, significant increase in liver LRP and NEP occurred much earlier, at 7 d, and were accompanied

35 PB1 A469T and a combination of NS1 N205K and NEP T48N) were identified as determinants of transmissib

36 B1 A469T, PA 1129T, NA N329D, NS1 N205K, and NEP T48N.

37 of the method enables us to quantify NMP and NEP metabolites at current environmental exposures by hu

38 N-Methyl- and N-ethyl-2-pyrollidone (NMP and NEP) are frequently used industrial solvents and were sh

39 th no known occupational exposure to NMP and NEP.

40 one or both of its encoded proteins (NS1 and NEP) are maladapted for replication in mammalian hosts.

41 consensus mutations in PB1, PA, NA, NS1, and NEP genes, additionally was able to confer respiratory d

42 The division of labor between PEP and NEP during plastid development and in mature chloroplast

43 vestigation into the distribution of PEP and NEP promoters within the plastid genome of barley (Horde

44 r photosynthesis proteins) have both PEP and NEP promoters.

45 ed global NPP (Net Primary Productivity) and NEP (Net Ecosystem Productivity) by 0.26 and 0.03 Pg C y

46 , and 57% of the variations in GPP, Re , and NEP, respectively.

47 However, the NEP/Re and NEP/GPP ratios exhibited little variability for inland w

48 mperature dependence of the responsivity and NEP of the GaN HEMT are also analyzed thoroughly.

49 Overall, NPP, Rh and NEP are regulated by highly interrelated effects of incr

50 erreported), and 2.2% reported not attending NEP but did attend (underreported).

51 459 (35%) had registered with the Baltimore NEP.

52 cycling technology (PCT), using a Barocycler NEP 2320 was compared with the conventional method using

53 Because NEP cleaves substrates other than Abeta, we investigated

54 ed NEP activation may be detrimental because NEP can degrade many physiological peptides, but its con

55 We also found an association between NEP and HRB in the perinuclear region, suggesting that N

56 NPs are mediated through interaction between NEP proteins and the cellular nucleocytoplasmic export m

57 lin, Notch, and Numb, were expressed by both NEP cells as well as other cell populations.

58 oid precursor protein and having one or both NEP genes silenced.

59 We now provide evidence that membrane-bound NEP is involved in the inactivation of tachykinin-relate

60 Abeta peptide-degrading enzyme in the brain; NEP becomes inactivated and down-regulated during both t

61 ere the most abundant fragments generated by NEP activity in vivo.

62 en GPCR and IGF-IR signaling is inhibited by NEP.

63 d metastases in PC cells can be regulated by NEP.

64 The influenza virus B and C NEP proteins interact in the yeast two-hybrid assay with

65 fferentiation of neuroepithelial stem cells (NEPs) to GRPs to ARPs and then to astrocytes.

66 g neural tube (E10.5, neuroepithelial cells; NEP) were examined for the expression of candidate stem

67 lerosis, to determine the effects of chronic NEP-I on plasma cGMP concentrations, vascular wall ECE-1

68 and increasing woody plant density decoupled NEP and ET from incident precipitation (P), resulting in

69 cific DPP-IV inhibitors have been developed, NEP 24.11 targets multiple sites in the GLP-1 sequence,

70 rter expression could be used to distinguish NEP stem cells from other dividing cells.

71 racellular A beta more effectively than does NEP in both the detergent-soluble and -insoluble fractio

72 ssibility that the NPY CTFs generated during NEP-mediated proteolysis might exert neuroprotective eff

73 elivery method, nanochannel electroporation (NEP), to produce predominantly nonendocytic uptakes of q

74 tein levels of nucleus- and plastid-encoded (NEP and PEP) components of the plastid transcriptional m

75 e degradation of SP to SP(1-4) by endogenous NEP in BM stroma could be a feedback on hematopoietic st

76 We asked whether a decrease in endogenous NEP levels can prolong the half-life of Abeta in vivo an

77 idase-IV (DPP-IV) and neutral endopeptidase (NEP) 24.11 severely compromises its effective clinical u

78 effect of oleacein on neutral endopeptidase (NEP) activity and other functions of human neutrophils,

79 expression identified neutral endopeptidase (NEP) and insulin-like growth factor binding protein-3 (I

80 ding enzyme (IDE) and neutral endopeptidase (NEP) are involved in the extracellular degradation of A

81 de (NP) receptors and neutral endopeptidase (NEP) in mediating and modulating the renal actions of De

82 identify a selective neutral endopeptidase (NEP) inhibitor as a potential treatment for FSAD.

83 Neutral endopeptidase (NEP) is expressed on normal prostate epithelium whereas

84 e SP-degrading enzyme neutral endopeptidase (NEP) is increased, compared to control skin.

85 ting enzyme (ACE) and neutral endopeptidase (NEP) may produce greater benefits in heart failure than

86 Neutral endopeptidase (NEP) uses SP as a substrate to produce SP(1-4), which in

87 cells, which express neutral endopeptidase (NEP), but not in androgen-independent prostate cancer (P

88 erence for Ang I, was neutral endopeptidase (NEP)-like.

89 rm oral inhibition of neutral endopeptidase (NEP).

90 to its resistance to neutral-endopeptidase (NEP) digestion.

91 campal neuronal cells (HT22) over-expressing NEP with the monomeric from of Abeta peptide decreases t

92 n the outer EGL and proliferate extensively, NEPs reside in the deep part of the EGL and are quiescen

93 restingly, the mRNA levels of endogenous fly NEP genes and phosphoramidon-sensitive NEP activity decl

94 year 2004 was climatologically favorable for NEP over North America and the continental total was est

95 slightly different distribution pattern for NEP was observed in the brain of L. migratoria.

96 dence for an evolutionary conserved role for NEP in the inactivation of tachykinin-related peptides i

97 Neurogenesis of neurons derived from NEP cells identified a second nestin non-expressing neur

98 Increasing precipitation accelerated GEP, NEP, microbial respiration, soil respiration, and ecosys

99 bon uptake (GEP) to the shrubland, grassland NEP was substantially less.

100 tudy, we investigated the effect of human (h)NEP gene transfer to the brain in a mouse model of AD be

101 and detrimental effects of chronically high NEP activity in the brain.

102 Using transgenic Drosophila expressing human NEP and Abeta42, we demonstrated that NEP efficiently su

103 al structure of LBQ657 in complex with human NEP at 2 A resolution.

104 ptor to ROCK in PC cells, and they implicate NEP as a major regulator of neuropeptide-stimulated RhoA

105 In NEP/NEP2 double-knockout mice, Abeta levels were margina

106 es in tau phosphorylation, and a decrease in NEP expression in the hippocampus that is coupled with a

107 GPP contributed equally to the difference in NEP between ENSO year 1998 and non-ENSO year 2000.

108 The spatial difference in NEP between low and high Arctic sites was determined mor

109 es do not lead to significant differences in NEP, which indicates that asymmetry in climate change do

110 with SCF, which correlated with increase in NEP messenger RNA.

111 cells, which lack NEP expression, but not in NEP-expressing LNCaP cells.

112 P co-immunoprecipitates with ERM proteins in NEP-expressing LNCaP prostate cancer cells and MeWo mela

113 A approximately 50% reduction in NEP levels, similar to that reported in some LOAD brains

114 orth America for the year 2004 that includes NEP as well as the additional emissions.

115 ory of metalloendopeptidases, which includes NEP and endothelin-converting enzyme 1 (ECE-1), an enzym

116 on, improved cognitive function and increase NEP activity in male APP23/Ar(+/-) mice compared with ag

117 Recombinant NEP and induced NEP expression in TSU-Pr1 cells using a tetracycline-rep

118 he site, which both stimulated and inhibited NEP depending upon phenology.

119 in with a concentration of 100 muM inhibited NEP activity, elastase, MMP-9 and IL-8 release from neut

120 Oleacein by inhibiting NEP activity, adhesion molecules expression and elastase

121 expression in mice treated with intravenous NEP, suggesting that the lack of effects in the brain fo

122 SU-Pr1, DU145, and PC-3 PC cells, which lack NEP expression, but not in NEP-expressing LNCaP cells.

123 ndent prostate cancer (PC) cells, which lack NEP expression.

124 sponsivity Rv of 15.5 and 2.7 kV/W and a low NEP of 0.58 and 10 pW/Hz(0.5) were obtained at room temp

125 re carbon sequestration as a result of lower NEP, it does not promote a metabolic release of current

126 interferes with the stability of the vRNP-M1-NEP nuclear export complex, probably mediated by its hig

127 cockroach peptide LemTRP-1 and the mammalian NEP substrate [DAla(2),Leu(5)]enkephalin at the Gly-Phe

128 rticles (MENPs) through nanoelectroporation (NEP) using alternating current (ac)-magnetic field stimu

129 o P, which resulted in a surprising negative NEP response to P.

130 Neprilysin (NEP) appears to be the most potent Abeta peptide-degradi

131 Neprilysin (NEP) is a naturally occuring enzyme that breaks down NPs

132 Neprilysin (NEP) is a zinc-dependent metalloprotease that is one of

133 Neprilysin (NEP) is an endopeptidase, which has an important role in

134 Neprilysin (NEP) is one of the rate-limiting Abeta-degrading enzymes

135 Neprilysin (NEP) is the dominant Abeta peptide-degrading enzyme in t

136 er prodrug of LBQ657, the active neprilysin (NEP) inhibitor, and a component of LCZ696 (sacubitril/va

137 Insulysin (IDE) and neprilysin (NEP) were found to be inactivated by oxidation with hydr

138 Abeta-degrading enzymes such as neprilysin (NEP) and insulin-degrading enzyme (IDE).

139 The endopeptidase neprilysin (NEP) is a major amyloid-beta (Abeta) degrading enzyme an

140 execution of two endopeptidases, neprilysin (NEP) and insulin-degrading enzyme.

141 ession of Abeta-degrading enzyme neprilysin (NEP) in primary neuronal cultures.

142 The Abeta-degrading enzyme neprilysin (NEP) is the best known target of these inhibitors.

143 A for the Abeta-degrading enzyme neprilysin (NEP) was found, whereas various Abeta-clearing and -degr

144 idney homogenates, we identified neprilysin (NEP) to be a major source of renal Ang-(1-7) in mice and

145 peptides by proteases, including neprilysin (NEP).

146 rane-bound Zn-metallopeptidases, neprilysin (NEP, EC 3.4.24.11) and aminopeptidase N (APN, EC 3.4.11.

147 nsulin-degrading enzyme (IDE) or neprilysin (NEP) in neurons significantly reduces brain Abeta levels

148 hat the Abeta-degrading protease neprilysin (NEP) is down-regulated in normal aging and LOAD.

149 and the Abeta-degrading protease neprilysin (NEP) occurred 14-21 d after a substantial decrease in br

150 The neprilysin (NEP)/endothelin-converting enzyme (ECE) family of metall

151 However, neuronal NEP overexpression reduced cAMP-responsive element-bindi

152 However, the protective effects of neuronal NEP expression on intraneuronal Abeta42 accumulation and

153 associate with wild-type NEP protein but not NEP protein containing a truncated cytoplasmic domain or

154 ective down-regulation of liver LRP, but not NEP, abrogated the therapeutic effects of the extract.

155 (split M segment [Ms]) or both M1/M2 and NS1/NEP (Ms and split NS segment [NSs]) open reading frames.

156 racteristics of influenza virus protein NS2 (NEP), which interacts with the nuclear export machinery

157 al ecosystem respiration (TER) and 25-80% of NEP.

158 However, genetic ablation of NEP results in only modest increases ( approximately 1.5

159 Decreasing the activity of NEP (due to genetic mutations, age or diseases that alte

160 ses that alter the expression or activity of NEP) may lead to accumulation of the neurotoxic Abeta pe

161 Intravenous administration of NEP to wild-type and APP23 transgenic mice resulted in d

162 The cytoplasmic domain of NEP contains a positively charged amino acid cluster, pr

163 r data suggest that the N-terminal domain of NEP interferes with the stability of the vRNP-M1-NEP nuc

164 In contrast, low and high doses of NEP inhibitor did not potentiate the renal actions of DN

165 hat EC and BM provide different estimates of NEP, but comparable ecosystem respiration and gross prim

166 nstrained peptides are the first examples of NEP 24.11-resistant GLP-1 analogues.

167 We conclude that over-expression of NEP by a gene therapy approach in areas vulnerable to Ab

168 In contrast, expression of NEP degraded the A beta in the detergent-insoluble fract

169 cy of lentivirus-mediated over-expression of NEP to protect neuronal cells from Abeta peptide in vitr

170 This suggests that these features of NEP are linked functionally.

171 d the question whether these two features of NEP are linked functionally.

172 This function of NEP represents a unique example of a proteolytic enzyme

173 llowed for the unambiguous identification of NEP promoters.

174 stent with this finding, immunoreactivity of NEP was increased in the hippocampus of AD mice.

175 morbidity further support the importance of NEP inhibition for augmenting natriuretic peptides as a

176 Inhibition of NEP enzyme activity using the specific NEP inhibitor CGS

177 Finally, pharmacologic inhibition of NEP resulted in strongly decreased Ang-(1-7) levels in m

178 and absence of long-term oral inhibition of NEP, together with assessment of atheroma formation.

179 sclerosis, were preserved with inhibition of NEP.

180 Thiorphan, an inhibitor of NEP, accumulated, albeit to a lesser extent, in insolubl

181 In contrast, intracranial injection of NEP resulted in an acute decrease in soluble brain Abeta

182 n normal prostate epithelium whereas loss of NEP expression contributes to PC progression.

183 fore, these data suggest that malfunction of NEP in infected macrophages may contribute to accelerati

184 conversion, models that included measures of NEP attendance based on self-reports compared with actua

185 We investigated the mechanisms of NEP regulation of neuropeptide-mediated cell survival in

186 two newly identified presumed metabolites of NEP, and their corresponding methyl counterparts (5-HNMP

187 extent to which differential misreporting of NEP attendance could bias risk estimates.

188 ons are mediated by the C-terminal moiety of NEP raised the question whether these two features of NE

189 Overexpression of NEP at low levels in transgenic (tg) mice affected prima

190 This was accompanied with great reduction of NEP endopeptidase activity, which might be due to the di

191 Down-regulation of NEP activity in aging brains may be an evolutionarily co

192 ar period from 1994 to 1997, self-reports of NEP attendance from participants in a prospective study

193 Since many studies rely on self-reports of NEP attendance, the authors investigated the extent to w

194 This unexpected new role of NEP may have implications for the combination therapy wi

195 Abeta, we investigated the potential role of NEP-mediated processing of neuropeptides in the mechanis

196 including whether neuropeptide substrates of NEP induce phosphorylations of IGF-IR and Akt in PC cell

197 might be due to the diminished transport of NEP to the cell surface and intracellular accumulation a

198 ptibility to proteolysis, while treatment of NEP with iron/ascorbate or hydrogen peroxide increased i

199 beta amyloid production and upregulation of NEP activities to enhance bate amyloid degradation.

200 Interannual variability of NEP, gross ecosystem production (GEP), and ecosystem res

201 ve important implications for evaluations of NEPs.

202 cate differential developmental potential of NEPs and NNEPs; NNEPs preferentially differentiate as ne

203 nding to the individual viral protein NS1 or NEP, without modifying the respective splicing and packa

204 unction is also performed by the orthologous NEP proteins (formerly referred to as the NS2 protein).

205 evations of Abeta, suggesting that yet other NEP-like Abeta-degrading endopeptidases are contributing

206 bridges provided outstanding shielding over NEP 24.11 (half-life of >96 h).

207 timating equations, persons who overreported NEP attendance were more likely to have injected frequen

208 ir broad range in the eastern North Pacific (NEP) and identified key environmental factors that influ

209 f the full virion and native empty particle (NEP) of RV-C15a.

210 a nuclear-encoded phage-type RNA polymerase (NEP), which recognize distinct types of promoters.

211 THz responsivity and noise equivalent power (NEP) of the device were characterized at 0.14 THz radiat

212 etion in nestin-expressing neural precursor (NEP) cells.

213 ifferentiated to neuroectodermal precursors (NEP), but not to epidermal (EPI) cells and found that tw

214 The presented NEP method can be adopted as a part of future nanotherap

215 ished estimates of net ecosystem production (NEP) and the produced map of young forests, this study e

216 predicted to alter net ecosystem production (NEP) by 64 gCm(-2) yr(-1).

217 k, calculations of net ecosystem production (NEP) defined as terrestrial only may be overestimated by

218 a(-1) yr(-1) lower net ecosystem production (NEP) during ENSO year 1998 compared with non-ENSO year 2

219 despite 79% lower net ecosystem production (NEP) following grazing (24.7 vs. 119.5 mmol C m(-2) d(-1

220 UEe , the ratio of net ecosystem production (NEP) to GPP, was estimated for each site using published

221 , with mean annual net ecosystem production (NEP) varying from -350 to +330 gCm(-2) across sites with

222 oduce estimates of net ecosystem production (NEP, the balance of net primary production and heterotro

223 nd the atmosphere (net ecosystem production, NEP) and its two components, ecosystem respiration and g

224 Net ecosystem production, NEP, is the net exchange of carbon dioxide (CO(2)) betwe

225 d a reduction of net ecosystem productivity (NEP) of about 6.1-9.3 Tg C y(-1) by 2009.

226 iration (Rh) and net ecosystem productivity (NEP) of six ecosystem types representing different clima

227 nts and seasonal net ecosystem productivity (NEP) proved largely compatible and suggested that carbon

228 nts and seasonal net ecosystem productivity (NEP) proved largely compatible and suggested that carbon

229 ation (Re ), and net ecosystem productivity (NEP) than inland wetlands.

230 olved organic C, net ecosystem productivity (NEP), and gross ecosystem productivity (GEP).

231 , which includes net ecosystem productivity (NEP), ecosystem respiration (ER) and gross ecosystem pho

232 cells, these Nestin-expressing progenitors (NEPs) are committed to the granule neuron lineage.

233 ave indicated that needle exchange programs (NEPs) can be effective in reducing drug-related risks fo

234 ural protein 1 (NS1)/nuclear export protein (NEP) for the modified NS segment were split by using the

235 Protein 1 (NS1), and Nuclear Export Protein (NEP) genes.

236 Intriguingly, the nuclear export protein (NEP) is involved in both processes.

237 with influenza virus nuclear export protein (NEP), during the influenza virus life cycle.

238 une evasion, and the nuclear export protein (NEP), required for the nuclear export of viral ribonucle

239 tein 1 (NS1) and the nuclear export protein (NEP).

240 he influenza A virus nuclear export protein (NEP, formerly referred to as the NS2 protein) mediates t

241 Recombinant NEP and induced NEP expression in TSU-Pr1 cells using a

242 -reported and actual NEP use; 11.0% reported NEP attendance but did not attend (overreported), and 2.

243 These data suggest that restoring NEP levels in the brain at the early stages of AD is an

244 red to other published estimates of seagrass NEP (median: 20.6 mmol C m(-2) d(-1)), NEP in grazed Car

245 ng with the clinically precedented selective NEP inhibitor, Candoxatrilat, and targeting low molecula

246 s fly NEP genes and phosphoramidon-sensitive NEP activity declined during aging in fly brains, as obs

247 ngs were supported by MALDI imaging, showing NEP mediated Ang-(1-7) formation in whole kidney cryo-se

248 ctivation of Sonic hedgehog (Shh) signaling, NEPs exhibited more severe genomic instability and gave

249 terminal fragments (CTFs), whereas silencing NEP reduced NPY processing.

250 These data suggest that SP, NEP, and NK-1R serve as important regulators in the mole

251 on of NEP enzyme activity using the specific NEP inhibitor CGS24592, or inhibition of PKCdelta using

252 In contrast, sustained NEP activation may be detrimental because NEP can degrad

253 As terrestrial NEP is the dominant offset to fossil fuel emission over

254 on fluxes within calculations of terrestrial NEP.

255 owever, Kell uses different amino acids than NEP in substrate binding and appears to have more flexib

256 We conclude that NEP can be used in infants to assess FL during forced ex

257 These experiments demonstrate that NEP can inhibit FAK phosphorylation on tyrosine and PC c

258 We also demonstrate that NEP inhibits neuropeptide activation of RhoA.

259 human NEP and Abeta42, we demonstrated that NEP efficiently suppressed the formation of intraneurona

260 We report here that NEP co-immunoprecipitates with ERM proteins in NEP-expre

261 In this study, we report that NEP has the dominant endopeptidase activity toward Abeta

262 We reported that NEP inhibits prostate cancer cell proliferation and cell

263 lated from E14.5 stage embryos, we show that NEP cells can be enriched by depleting differentiating c

264 In vitro binding assays showed that NEP binds directly to recombinant N terminus fragments o

265 ved lentiviral vector injections showed that NEP cleaved NPY into C-terminal fragments (CTFs), wherea

266 These data suggest that NEP can affect cell adhesion and migration through direc

267 B in the perinuclear region, suggesting that NEP may contribute to this process.

268 Expression profiling revealed that NEPs are distinct from GNPs and, in particular, express

269 The NEP was performed in microglial (MG) brain cells, which

270 The enzyme was acted upon by the NEP inhibitors phosphoramidon (IC(50), 0.64 microM) and

271 ferentiation of glial cells derived from the NEP cells was significantly decreased with no compensati

272 ion for the loss of neurons derived from the NEP pool by the NNEP pool but this was insufficient to a

273 However, the NEP/Re and NEP/GPP ratios exhibited little variability f

274 cross disparate oceanographic regions in the NEP and increased utilization of deeper waters in offsho

275 d miR-96, were uniquely downregulated in the NEP cells.

276 Of particular interest is the NEP homolog neprilysin 2 (NEP2), which is thiorphan/phos

277 remaining 6 dogs received an infusion of the NEP inhibitor, candoxatrilat (8 and 80 microg/kg/min) (P

278 counteracted a large proportion (35%) of the NEP sink.

279 ction between M1 and the vRNP depends on the NEP C terminus and its polymerase activity-enhancing pro

280 dy to determine its breadth and potency, the NEP server can be used to predict antibody-epitope infor

281 renal actions of synthetic DNP and that the NEP inhibitor did not alter the renal response to DNP.

282 flexible intramolecular interaction with the NEP C terminus.

283 tively charged amino acid cluster within the NEP cytoplasmic domain.

284 The synthetic analogues modified within the NEP degradation site ("RPRL" motif) showed improved in v

285 Because the NEPs also display these fingers, they may have utility a

286 Binding of ERM proteins to NEP results in decreased binding of ERM proteins to the

287 Similar to NEP, the Kell protein has 2 globular domains consisting

288 Moreover, cells expressing wild-type NEP demonstrate decreased adhesion to hyaluronic acid an

289 d that ERM proteins associate with wild-type NEP protein but not NEP protein containing a truncated c

290 Most of the unexplained NEP variability was related to persistent, site-specific

291 riparian sites increased net carbon uptake (NEP) and evapotranspiration (ET), which were sustained o

292 ated in the absence of the influenza B virus NEP protein were unable to transfer the viral RNA-like C

293 for cell entry in contact exposure, whereas NEP delivery of nanoparticles bypassed endocytosis.

294 erentially differentiate as neurons, whereas NEPs give rise to both neurons and glial cells.

295 y in Baltimore, Maryland, were compared with NEP records.

296 approximately 1.5- to 2-fold), compared with NEP(-/-)/NEP2(+/+) controls.

297 ant Kell proteins analyzed and compared with NEP.

298 tic versus normal rabbits and preserved with NEP inhibition, which also decreased atheroma formation.

299 mplications for the combination therapy with NEP-inhibitors and angiotensin-receptor-blockade, which

300 Woodland NEP was large, but surprisingly similar to the less matu